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Bacterial Genetics
Why do genetics in bacteria?
- haploid so there are no problems with dominance
- they have many fewer genes than eukaryotes
(<5,000)
- small and fast growing - good for statistics and
studying rare events
- you can isolate clones
- they are responsible for many diseases
- economically important (biotech, agricultural
diseases, novel biochemical products and reactions)
How do you do genetics in bacteria?
- Luria and Delbruck (1943)
- are bacterial variants adaptations or mutations?
- used a fluctuation test
How to get DNA transfer and recombination? Bacteria do
not have meiosis and eukaryotic sexual reproduction.
However, they do have many different mechanisms for
exchanging genes between individuals, including
transformation, conjugation, sexduction and transduction.
These mechanisms can be used by a geneticist to study
bacterial genes.
Bell
CSU Chico
Library
This document is copyright of
Jeff
Bell
Last Update: Wednesday, August 12, 1998
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